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High Fat Diet and Colorectal Cancer

Published on: 9 Nov, 2023
New research has shown how a high fat diet may increase the risk of developing colon cancer. It appears that mice being fed a high fat diet experienced an increase in the population of gut bacteria that resulted in an alteration of bile acids in a way that increases inflammation and prevents intestinal stem cells from replenishing. This process ultimately prevented the effective repair of damaged cells, allowing damaged cells to divide and multiply, resulting in precancerous lesions in the colon. The high fat diet seems to have a greater impact on colorectal cancer risk than the mice’s genetic predisposition to colorectal cancer. Though human clinical studies are still needed to confirm the study findings, experts recommend that limiting intake of high fat foods would be a beneficial step in reducing the risk of colon cancer.
 
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High Risk Polyps and Liver Cancer

Published on: 5 Oct, 2023

A research study based in Austria suggests that people who have had high risk polyps discovered on screening colonoscopy are also at increased risk of developing liver cancer in the future. Polyps that are greater than 10mm, adenomas with high grade dysplasia, serrated adenomas with dysplasia, or 5 or more adenomas meet the definition of "high risk” and increase a patient’s risk of developing colon cancer in the future if regular surveillance isn’t carried out. Now, it appears that patients who have had high risk polyps at screening colonoscopy go on to experience a liver cancer mortality rate that is more than twice as high as that of their peers who have had a negative screening colonoscopy. While it is clear that liver and colon cancer share some common risk factors, there are currently no targeted combined screening and surveillance programs. 

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NAFLD and Colon Cancer

Published on: 7 Sep, 2023
A recently published study has revealed that the presence of nonalcohol fatty liver disease (NAFLD) is an independent risk factor for the development of adenomatous colon polyps, which are precursors to colorectal cancer. This association is observed in both men and women. These findings may shed new light on the prevention of colon cancer in this group of patients, and may influence guidelines and recommendations for colon cancer screening in the future. 
 

Dyspepsia: What you need to know

Published on: 6 Jul, 2023
Dyspepsia, or indigestion, is a relatively common complaint, affecting up to 30% of the population. It is not a disease, but rather a symptom of other medical conditions or related to certain types of medications. Symptoms may include pain or discomfort after eating, feeling too full after eating, bloating, nausea, or heartburn. Some simple lifestyle changes may be effective in mild cases, while medication may be needed in more severe cases. People who experience severe abdominal pain, weight loss, bleeding from the digestive tract, anemia, difficulty swallowing, or general feeling of unwellness, in addition to indigestion, should always consult a physician in order to rule out a more serious underlying problem. 
 
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H. Pylori: What is it?

Published on: 6 Jun, 2023
Helicobacter pylori, or H. pylori, is a bacteria that can affect the stomach and small intestine, potentially causing inflammation and ulcers in the short term, and increasing the risk of stomach cancer in the long term. H. pylori itself doesn’t cause symptoms, but the complications it causes do, though they can be vague and caused by a variety of problems. Patients suffering from an ulcer may complain of a burning pain in their stomach, which may temporarily improve with food or antacids, while inflammation in the stomach can cause nausea, vomiting, and pain. Once H. pylori is confirmed, treatment is relatively simple, usually involving antibiotics and a proton pump inhibitor. With quick and appropriate treatment, further damage to the stomach can be prevented.

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