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March is Colorectal Cancer Awareness Month!

Published on: 4 Mar, 2024
- It is estimated that 1 in 16 Canadian men and 1 in 18 Canadian women will be diagnosed with colorectal cancer in their lifetime
- On average, 66 Canadians are diagnosed with colorectal cancer every day
- The risk of developing colorectal cancer seems to increase as birth cohorts get progressively younger, and people born in the early 1990s are at almost three times the risk of developing colon cancer as their parents and grandparents
- Colorectal cancer is the 2nd leading cause of death in men and the 3rd leading cause of death in women
- Signs and symptoms of colorectal cancer include rectal bleeding, change in bowel habits, abdominal pain, weight loss, and anemia, among others, but many people experience no symptoms whatsoever. That is why screening is so vital!
- Of all the different types of cancer in Canada, colorectal cancer rates are declining the fastest. This is due to increased awareness of symptoms and increased rates of screening
- Risk factors include having a family or personal history of colorectal cancer, being over the age of 50, having inflammatory bowel disease such as Crohn’s or Ulcerative Colitis, or having inherited genetic syndromes such as Lynch syndrome
- With proper screening and early treatment, colorectal cancer is preventable, treatable, and beatable!
 

CRC Risk Increasing Across Successive Birth Cohorts

Published on: 9 Feb, 2024
A disease that used to affect mostly older adults is now becoming increasingly common in adults below the age of 60. New studies have shown that the risk of developing colon cancer is increasing in successive birth cohorts. People born between 1990 and 1994 now have a nearly 3-fold increase in risk when compared to people born 40 years earlier, and colorectal cancer rates have increased most rapidly in the 30-49 age group. Increasing awareness of red-flag symptoms and the importance of screening is critically important for all age groups, but particularly for the under-45 age group, as is ongoing education about risk factors. 
 

High Fat Diet and Colorectal Cancer

Published on: 9 Nov, 2023
New research has shown how a high fat diet may increase the risk of developing colon cancer. It appears that mice being fed a high fat diet experienced an increase in the population of gut bacteria that resulted in an alteration of bile acids in a way that increases inflammation and prevents intestinal stem cells from replenishing. This process ultimately prevented the effective repair of damaged cells, allowing damaged cells to divide and multiply, resulting in precancerous lesions in the colon. The high fat diet seems to have a greater impact on colorectal cancer risk than the mice’s genetic predisposition to colorectal cancer. Though human clinical studies are still needed to confirm the study findings, experts recommend that limiting intake of high fat foods would be a beneficial step in reducing the risk of colon cancer.
 
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High Risk Polyps and Liver Cancer

Published on: 5 Oct, 2023

A research study based in Austria suggests that people who have had high risk polyps discovered on screening colonoscopy are also at increased risk of developing liver cancer in the future. Polyps that are greater than 10mm, adenomas with high grade dysplasia, serrated adenomas with dysplasia, or 5 or more adenomas meet the definition of "high risk” and increase a patient’s risk of developing colon cancer in the future if regular surveillance isn’t carried out. Now, it appears that patients who have had high risk polyps at screening colonoscopy go on to experience a liver cancer mortality rate that is more than twice as high as that of their peers who have had a negative screening colonoscopy. While it is clear that liver and colon cancer share some common risk factors, there are currently no targeted combined screening and surveillance programs. 

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